The hormone replacement therapy debate
Hormone replacement therapy is a well-established risk factor for breast cancer, and in my little world of breast cancer epidemiology the use of hormone replacement therapy seemed inconceivable. And then I started thinking … the effect size of hormone replacement therapy on breast cancer risk might not be large enough to justify depriving individual women from an easier transition to menopause (less depression, normal sexual drive, fewer fractures, lower risk of CHD, etc.) on a case-by-case basis. Continue reading
